Does Polycythemia Cause Bone Pain?

PV causes blood to be thicker than normal due to high levels of red blood cells and platelets. If you have PV and leg pain, a clot may be the cause.

What are the side effects of polycythemia vera?

What are the symptoms of polycythemia vera?

  • Lack of energy (fatigue) or weakness.
  • Headache.
  • Dizziness.
  • Shortness of breath and trouble breathing while lying down.
  • Vision problems, such as double vision, blurred vision, and blind spots.
  • Inability to concentrate.
  • Night sweats.
  • Face and becomes red and warm (flushed)

What are the symptoms of PV disease?


  • Itchiness, especially after a warm bath or shower.
  • Numbness, tingling, burning, or weakness in your hands, feet, arms or legs.
  • A feeling of fullness soon after eating and bloating or pain in your left upper abdomen due to an enlarged spleen.
  • Unusual bleeding, such as a nosebleed or bleeding gums.

What is PV itching?

Itchy skin is a common symptom of some other blood cancers. Research has shown that people with PV tend to have higher levels of mast cells in their blood. Mast cells are involved in the immune system’s allergic response. They release histamines, which cause allergic symptoms, including itching skin.

What are two conditions that cause polycythemia?

What are the risk factors for polycythemia?

  • Hypoxia from long standing (chronic) lung disease and smoking are common causes of polycythemia. …
  • Chronic carbon monoxide (CO) exposure can also be a risk factor for polycythemia.

What should I eat if I have polycythemia?

In general, the guidelines for people with PV are the same as for everyone else: eat a low-fat diet in sensible portions with fruits, vegetables, grains and legumes. Drink plenty of fluids. It’s important to stay well hydrated to keep your blood from thickening.

Does polycythemia get worse?

It usually happens during the later stages of the disease. Polycythemia vera treatments help reduce your risk of symptoms and complications. But for some people, the disease still gets worse and turns into another blood cancer, despite treatment.

Does polycythemia go away?

There’s no cure for polycythemia vera. Treatment focuses on reducing your risk of complications. These treatments may also ease your symptoms.

Can PV cause back pain?

Bone pain as the presenting symptom in polycythemia vera (PV) is rare, especially without the diagnosis of myelofibrosis (MF). Pain, however, can manifest as a late symptom in approximately 50% of patients with the diagnosis. The cause of pain has been attributed to hematopoiesis, periostitis, and osteosclerosis.

Does PV affect the liver?

Some individuals with polycythemia vera have developed Budd-Chiari syndrome, a condition in which a blood clot forms in the main blood vessel leading to the liver (hepatic vein thrombosis).

Does liver cause polycythemia?

Manganese accumulation in the liver can lead to an enlarged liver (hepatomegaly) and scarring of the liver (i.e., cirrhosis). Individuals with this condition often also have an accumulation of too many red blood cells (polycythemia) in the bloodstream.

What is the difference between polycythemia and polycythemia vera?

Secondary polycythemia is defined as an absolute increase in red blood cell mass that is caused by enhanced stimulation of red blood cell production. In contrast, polycythemia vera is characterized by bone marrow with an inherent increased proliferative activity.

Which is worse PV or ET?

In a very recent publication, researchers at the Mayo Clinic reported worse survival for patients with PV (median, 15 years) than those with ET (median, 18 years, p < 0.05), but similar leukemia-free survival (p = 0.22).

How long does polycythemia last?

Median survival in patients with polycythemia vera (PV), which is 1.5-3 years in the absence of therapy, has been extended to approximately 14 years overall, and to 24 years for patients younger than 60 years of age, because of new therapeutic tools.

How many people have died from polycythemia vera?

Mortality Rates in Polycythemia Vera

Overall 244 patients (9.7%) have died during the study, and at last follow-up 90% were alive. The 4-year mortality rate for PV was estimated to be more than 10%. The average age at death was 77.1 years with a mean disease duration of 8.6 years.

Can you live a full life with polycythemia vera?

Polycythemia vera (PV) is a rare blood cancer. While no cure exists for PV, it can be controlled through treatment, and you can live with the disease for many years.

Can you live a normal life with polycythemia?

If well controlled, polycythaemia should not affect your life expectancy, and you should be able to live a normal life. However, people with PV can have a slightly lower life expectancy than normal due to the increased risk of problems, such as heart attacks and strokes.

Is coffee good for polycythemia?

Taking a cup of caffeinated coffee as part of the diet may be beneficial for reducing the risk of polycythemia vera.

What is the most common cause of polycythemia?

Primary polycythemia is genetic. It’s most commonly caused by a mutation in the bone marrow cells, which produce your red blood cells. Secondary polycythemia can also have a genetic cause. But it’s not from a mutation in your bone marrow cells.

How do you treat polycythemia naturally?

In addition to your medical plan, use these self-care tips to help you feel better:

  1. Exercise daily. Staying active will help keep your blood flowing and prevent clots. …
  2. Take cool baths to prevent skin irritation. …
  3. Keep warm. …
  4. Drink a lot of water. …
  5. Try not to hurt your feet. …
  6. Treat itchy skin. …
  7. Shield your skin from the sun.

Is polycythemia vera considered a disability?

If you suffer from polycythemia vera, which is a serious disease that can result in death, you may be unable to work. In those situations, you may qualify for Social Security disability benefits.

How is polycythemia detected?

To diagnose PV, your doctor will perform a test called a complete blood count (CBC) to see if your number of red blood cells is higher than normal. Your doctor may also test your blood to look for amounts of a hormone called erythropoietin. Lower-than-normal levels of this hormone can be a sign of PV.

Does polycythemia affect immune system?

Interestingly, several studies addressing the characterization of immune cells suggest that people with PV have changes in the percentage of T and NK lymphocytes, two population of white blood cells present in the blood circulation and involved in the elimination of mutated and malignant cells, like the bone marrow …