Pyruvate decarboxylase (PDC, EC 4.1. 1.1) is the enzyme responsible for the non-oxidative decarboxylation of pyruvate to acetaldehyde and carbon dioxide. How is pyruvate decarboxylase regulated? Pyruvate decarboxylation is an irreversible process that commits the pyruvate derivative to the citric acid cycle. The enzyme that catalyzes this process, called theRead More →