What medicines should you avoid during pregnancy? Bismuth subsalicylate (such as Pepto-Bismol). Phenylephrine or pseudoephedrine, which are decongestants. … Cough and cold medicines that contain guaifenesin. … Pain medicines like aspirin and ibuprofen (such as Advil and Motrin) and naproxen (such as Aleve). What lozenges can you have when pregnant?Read More →