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At present, evidence of two major pathways is found. One is that the vesicle is formed on the membrane surface, either at the plasma membrane at the cell surface or at internal cell organelles like the TGN. Another possibility is that vesicles formed elsewhere dock at, fuse with, and thenRead More →

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Transport vesicles Membrane-bound and secreted proteins are made on ribosomes found in the rough endoplasmic reticulum. Most of these proteins mature in the Golgi apparatus before going to their final destination which may be to lysosomes, peroxisomes, or outside of the cell. Are lysosomes secretory vesicles? The mannose 6-phosphate receptorRead More →